The text is a practical guide to the six chakras (Muladhara to Ajna). It describes:

Before we proceed to the solution, it is important to address the hurdles:

One of the most famous sections of the Rudrayamala deals with the Dasha Mahavidyas—the ten forms of the Goddess (Kali, Tara, Tripura Sundari, Bhuvaneshwari, Bhairavi, Chhinnamasta, Dhumavati, Bagalamukhi, Matangi, and Kamala). The text provides their specific yantras, mantras, and sadhana procedures.