Assuming you’ve found a verified repack (e.g., FitGirl’s version), here’s a typical installation:
Yes, but only if you are careful.
The GTA San Andreas remastered PC download repack highly compressed version is the definitive way to play on a low-end laptop or a handheld device. The community has done a better job fixing San Andreas than Rockstar did with the official Trilogy.
However, if you have a modern gaming rig and a stable internet connection, you are better off:
This gives you 95% of the "remastered" look with zero malware risk.
Remaster has physics tied to frame rate. Use NVIDIA Control Panel or RivaTuner to cap.