Amd Registry Tweaks Portable May 2026

AMD’s drivers store their configuration in two primary locations:

HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\Class\4d36e97d-e325-11ce-bfc1-08002be10318\0000

HKEY_CURRENT_USER\Software\AMD\AMDCanvas & HKEY_CURRENT_USER\Software\AMD\AMDDVR

Warning: Always export (backup) the key before editing. For portable use, keep a backup.reg file on the same USB drive.

examples/ (sample logs)

Instead of hunting for keys manually, here is the complete portable script for all AMD GPUs (RX 400 to RX 7000) and Ryzen CPUs. amd registry tweaks portable

File: AMD_Portable_Optimal.reg

Windows Registry Editor Version 5.00
; ===============================
; AMD GPU LATENCY FIXES
; ===============================
[HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\Class4d36e968-e325-11ce-bfc1-08002be10318\0000]
"EnableUlps"=dword:00000000
"DisableDrmdmaPowerGating"=dword:00000001
"DisableDynamicSlicePowerGating"=dword:00000001
"PP_ThermalAutoThrottlingEnable"=dword:00000000
[HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\Class4d36e968-e325-11ce-bfc1-08002be10318\0000\DalRendering]
"RIS_Enable"=dword:00000001
"RIS_Strength"=dword:00000050
; ===============================
; DISABLE MPO (Flicker Fix)
; ===============================
[HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Windows\Dwm]
"OverlayTestMode"=dword:00000005 AMD’s drivers store their configuration in two primary
; ===============================
; DXNAVI LATENCY REDUCTION (RDNA2/3)
; ===============================
[HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\GraphicsDrivers]
"TdrDelay"=dword:00000008
"TdrDdiDelay"=dword:00000005
[HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\Session Manager\Memory Management]
"LargeSystemCache"=dword:00000001

Save this as a .reg file. Double-click. Reboot. You are now running a fully portable, no-installation AMD optimization suite. Hex 64 = 100% sensitivity

Useful for laptops or portable setups where power/heat management is critical.

Note: You may need to set Min/Max FPS values in sub-keys or the Adrenalin software once to calibrate it, but this registry switch toggles the feature on/off globally.

While Radeon Boost lowers resolution during fast mouse movement, you can tweak its sensitivity.

Portable Code:

[HKEY_CURRENT_USER\Software\AMD\D3D\RadeonBoost]
"Sensitivity"=dword:00000064  ; Hex 64 = 100% sensitivity